I think it is time for finally dropping some old platforms. Major opensource projects like Chrome are now dropping Windows XP support, therefore I think it is time to remove last bits of pre-WinXP support too (I believe that theide could now actually still run in Win2K...)
It would our life much easier if we moved this to at least Windows Vista - Vista API has some really good improvements in multithreading. Do we still need to support WinXP?
In related news, I plan to fully embrace C++11 and drop support for pre-C++11 (I mean, I want to start using C++11 constructs all over the place and stop worrying with old C++ variants).